necrosis Image

sheets of cells Image

synctial cells- the morphological appearance raises the possibility of lymphoid depleted HD but also non-Hodgkin's anaplastic large cell lymphoma and synctial variant of HD Image

irregular multinucleated cells Image

pleomorphic large cells with vesicular chromatin; by flow these cells are negative for B and T cell markers Image

large cells have CD15; they lack CD20 and CD3 Image

Diffuse EBV positivity; patient has no history of immunosupression but patient did receive hydroxyurea for polycythemia vera Image