System: Mediastinum: Thymus: Neoplastic: Liposarcoma
well differentiated liposarcoma as shown here is the most common subtype of liposarcoma in this area - this may represent the inflammatory variant of well-differentiated liposarcoma with lymphoid aggregates Image
dark cells and adipocytes Image
is that a lipoblast Image
Most common sarcoma in the anterior mediastinum.
Affects adults. THere may be syncronous involvement of other sites such as retroperitoneum. In a review of 24 cases, patients ranged from 3 years to 72 years of age, with a median age of 58 years. Presenting symptoms were most commonly dyspnea (5 cases), and cough (4 cases) (Hahn).
Curable upon resection but approximately 1/3 recur.
Hahn HP, Fletcher CD. Primary mediastinal liposarcoma: clinicopathologic analysis of 24 cases. Am J Surg Pathol. 2007 Dec;31(12):1868-74.