System: Hematopathology: Lymph Nodes: Neoplastic: Diffuse Large B Cell Lymphoma, Anaplastic Variant
large pleomophic cells which appear somewhat cohesive, growing in a sinusoidal pattern Image
irregular nuclei, cytoplasm, many mitotic figures Image
cells are CD20 positive (not shown) and stain for bcl-2 Image
and bcl6 Image
cd79a also positive as seen here in many but not all of the pleomorphic cells; not shown but CD30 is also positive Image