sheets of large cells with prominent nucleoli resembling poorly differentiated carcinoma Image

this tumor resembles other epithelioid lesions, such as extrarenal rhabdoid tumor, epithelioid angiosarcoma and melanoma; has a rhaboid appearance Image

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IN1 1 loss is characteristic of both regular and proximal type epithelioid sarcoma (Hornick). The inflammatory cells in the background show normal nuclear staining. Image

EMA --- positive in about 85% of cases. while many sarcomas can have cytoplasmic EMA, this tumor along with synovial sarcoma, show nice membrane postivitiy. Focal cytoplasmic staining for muscle markers, either desmin or alpha-smooth muscle actin (SMA), S-100 protein, neurofilament, neuron-specific enolase, synaptophysin, and CD56 may be found in a minority of cases. Image

CAM 5.2; this is one of the tumors that co-expresses both vimentin and keratin Image

predominantly in the deep soft-tissue or subcutis of young adults or middle-aged individuals and had a significant male predominance

The rate of tumor-related deaths is lower than the rate of metastasis (75%), suggesting an indolent yet persistent nature for this tumor. Important adverse prognostic factors are larger tumor sizeand early metastasis, the latter independently correlating with clinical aggressiveness.